Spinach Artichoke Chicken Bake

Featured in: Oven & Pan Cooking

This comforting bake combines juicy chicken breasts with a rich, tangy topping inspired by classic spinach artichoke dip. The creamy mixture features fresh spinach, tender artichoke hearts, Greek yogurt, mozzarella, and Parmesan for a protein-packed dinner that's naturally gluten-free.

Ready in just 45 minutes with only 15 minutes of prep, this dish comes together quickly for busy weeknights. Simply season the chicken, sauté the garlic and spinach until wilted, then mix with chopped artichokes and cheeses before spreading over the chicken and baking until golden.

The result is tender, flavorful chicken with a bubbly, savory topping that pairs perfectly with rice, quinoa, or a crisp green salad. Leftovers reheat beautifully for meal prep.

Updated on Wed, 21 Jan 2026 08:33:00 GMT
A close-up of golden, bubbly Spinach & Artichoke Chicken Bake fresh from the oven, served over a bed of fluffy white rice.  Save to Pinterest
A close-up of golden, bubbly Spinach & Artichoke Chicken Bake fresh from the oven, served over a bed of fluffy white rice. | maisonizer.com

I stumbled across this idea during one of those pantry clean-out evenings when I had chicken breasts that needed cooking and a random assortment of dairy products. The Greek yogurt substitution happened by accident, and honestly, it made the whole dish lighter while keeping that creamy comfort I was craving. My husband took one bite and asked why I'd been hiding this recipe from him.

My sister came over unexpectedly that first night I made this, and she ended up eating two servings straight from the baking dish. We stood in the kitchen leaning against the counter, just talking and picking at the leftovers. Sometimes the best dinners are the ones that happen without any planning at all.

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Ingredients

  • Boneless skinless chicken breasts: Pounding them to even thickness helps everything cook uniformly without drying out the thinner edges
  • Fresh baby spinach: Frozen spinach works too, but fresh gives you that bright green color and none of that weird metallic aftertaste
  • Canned artichoke hearts: Draining them well and patting dry prevents the topping from becoming watery during baking
  • Plain Greek yogurt: Whole milk version makes the biggest difference in texture and mouthfeel
  • Shredded mozzarella: Creates those gorgeous bubbly golden patches everyone fights over at the table
  • Grated Parmesan: Adds that salty umami punch that ties everything together

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Instructions

Get your oven ready:
Preheat to 400°F and grease a 9x13 baking dish with a little olive oil or cooking spray
Season the chicken:
Sprinkle both sides with salt and pepper, then arrange in a single layer in your prepared dish
Sauté the aromatics:
Heat olive oil in a skillet over medium heat, cook garlic for 30 seconds until fragrant, then add spinach and wilt for about 2 minutes
Make the topping mixture:
Combine the sautéed spinach, chopped artichokes, Greek yogurt, mozzarella, Parmesan, oregano and red pepper flakes in a bowl
Top and bake:
Spread the mixture evenly over each chicken breast and bake for 25-30 minutes until the chicken reaches 165°F internally
Rest before serving:
Let everything sit for 5 minutes so the juices redistribute and the topping sets slightly
Baked chicken breasts topped with creamy spinach and artichoke mixture, paired with a crisp green salad for a healthy dinner.  Save to Pinterest
Baked chicken breasts topped with creamy spinach and artichoke mixture, paired with a crisp green salad for a healthy dinner. | maisonizer.com

This became our go-to when friends have new babies or need a meal dropped off. It travels well, reheats beautifully, and feels like something you'd order at a restaurant. My neighbor started requesting it for her birthday dinner instead of going out.

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Make It Your Own

Swap half the Greek yogurt for cream cheese if you want an even richer finish. Add sun-dried tomatoes or sautéed mushrooms directly into the topping mixture. A sprinkle of extra shredded mozzarella during the last 5 minutes creates that restaurant-quality cheese pull everyone loves.

Serving Ideas

Crisp roasted green beans or asparagus balance the creamy topping perfectly. A simple quinoa or rice pilaf soaks up any extra sauce. For a lighter meal, serve alongside a big green salad with a bright vinaigrette that cuts through the richness.

Storage & Reheating

Leftovers keep beautifully in the refrigerator for up to three days, making it perfect for meal prep. Reheat individual portions in the microwave at 50% power to prevent the topping from separating. The texture actually improves overnight as the flavors meld together.

  • Freeze portions in airtight containers for up to 3 months
  • Thaw overnight in the refrigerator before reheating
  • Add a splash of water when reheating to restore creaminess
Slice into tender Spinach & Artichoke Chicken Bake revealing juicy chicken layered with creamy, tangy spinach and artichoke topping. Save to Pinterest
Slice into tender Spinach & Artichoke Chicken Bake revealing juicy chicken layered with creamy, tangy spinach and artichoke topping. | maisonizer.com

Sometimes the simplest weeknight dinners become the ones we make on repeat forever.

Recipe Q&A

Can I use frozen spinach instead of fresh?

Yes, thaw and drain frozen spinach thoroughly before using. Squeeze out excess moisture to prevent the topping from becoming watery. One 10-ounce package of frozen spinach equals about 2 cups fresh.

What can I substitute for Greek yogurt?

Sour cream, light cream cheese, or plain regular yogurt all work well. For a dairy-free option, try a creamy coconut yogurt or cashew cream, though the flavor profile will change slightly.

How do I know when the chicken is done?

Use a meat thermometer to check that the internal temperature reaches 165°F (74°C) in the thickest part of the breast. The topping should be golden brown and bubbling, and the chicken should feel firm when pressed.

Can I prepare this ahead of time?

Yes, assemble the dish up to 24 hours in advance and refrigerate covered. You may need to add 5-10 minutes to the baking time if baking cold from the refrigerator.

What sides pair well with this dish?

Rice, quinoa, roasted potatoes, or crusty bread soak up the creamy topping. A crisp green salad with vinaigrette balances the richness. Roasted vegetables like broccoli or asparagus also complement beautifully.

Can I use chicken thighs instead of breasts?

Absolutely. Boneless, skinless thighs work wonderfully and stay juicy. Adjust baking time to 30-35 minutes, checking for an internal temperature of 165°F.

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Spinach Artichoke Chicken Bake

Tender chicken baked under a creamy, cheesy spinach and artichoke topping. Ready in 45 minutes.

Time to Prep
15 mins
Time to Cook
30 mins
Time Needed
45 mins
Created by Clint Rodriguez


Skill Level Easy

Cuisine American

Portions 4 Number of Servings

Diet Details No Gluten, Low in Carbs

What You Need

Chicken

01 4 boneless skinless chicken breasts (about 1.5 lbs)
02 1/2 teaspoon kosher salt
03 1/4 teaspoon freshly ground black pepper

Spinach & Artichoke Topping

01 1 tablespoon olive oil
02 2 cups fresh baby spinach, roughly chopped
03 1 (14 oz) can artichoke hearts, drained and coarsely chopped
04 2 cloves garlic, minced
05 1 cup plain whole milk Greek yogurt
06 1/2 cup shredded mozzarella cheese
07 1/4 cup grated Parmesan cheese
08 1/4 teaspoon dried oregano
09 1/4 teaspoon crushed red pepper flakes

How-To Steps

Step 01

Preheat oven and prepare baking dish: Preheat oven to 400°F. Lightly grease a 9x13-inch baking dish with cooking spray or a small amount of olive oil.

Step 02

Season chicken: Pat chicken breasts dry with paper towels. Season both sides evenly with kosher salt and black pepper. Arrange in a single layer in the prepared baking dish.

Step 03

Sauté aromatics and spinach: Heat olive oil in a skillet over medium heat. Add minced garlic and sauté for 30 seconds until fragrant. Add chopped spinach and cook, stirring occasionally, until just wilted, about 2 minutes. Remove from heat.

Step 04

Prepare topping mixture: In a mixing bowl, combine the sautéed spinach mixture, drained chopped artichoke hearts, Greek yogurt, shredded mozzarella, grated Parmesan, dried oregano, and crushed red pepper flakes. Stir until thoroughly combined.

Step 05

Top chicken and bake: Spread the spinach and artichoke mixture evenly over each chicken breast, covering completely. Bake for 25 to 30 minutes until chicken reaches an internal temperature of 165°F and topping is golden and bubbly.

Step 06

Rest before serving: Remove from oven and let rest for 5 minutes before serving to allow juices to redistribute.

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Equipment List

  • 9x13-inch baking dish
  • Skillet or frying pan
  • Mixing bowl
  • Chef's knife and cutting board
  • Measuring cups and spoons
  • Meat thermometer

Allergy Details

Always review every ingredient for allergens. Talk to your healthcare provider if you’re unsure.
  • Contains dairy (Greek yogurt, mozzarella, Parmesan)
  • May contain eggs if using egg-enriched cheese varieties
  • Gluten-free as written; verify labels for cross-contamination if sensitive

Nutrition Info (per portion)

Nutritional info is for reference and isn’t medical advice.
  • Caloric value: 325
  • Fats: 11 g
  • Carbohydrates: 7 g
  • Proteins: 48 g

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